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Cynar was created by Venetian entrepreneur Angelo Dalle Molle in 1952. It grew to prominence in Italy in the 1960s thanks to a series of TV ad featuring the famous Italian actor, Ernesto Calindri.

Cynar is made from a blend of 13 herbs and botanicals, chief amongst which is artichoke, which features prominently on the bottle and even gives its latin name, Cynara scolymus, to the name of the drink.